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Research Fellow (UCL Cancer Institute) at UCL
London, United Kingdom
Job Descrption
The UCL Cancer Institute is the hub for cancer research at University College London, one of the World's leading universities. The Institute draws together over 400 talented scientists who are working together to translate research discoveries into developing kinder, more effective therapies for cancer patients. In particular, it fosters links between basic cancer researchers across Biomedicine and with the clinical activities of our four partner hospital trusts, known as UCL Partners (University College London Hospital NHS Foundation Trust, Great Ormond Street Hospital for Children NHS Trust, the Royal Free Hampstead NHS Trust, and Moorfields Eye Hospital NHS Foundation Trust), as well as the London School of Pharmacy and Cancer Research UK.
The Institute has greater clinical links than any comparable centre in the UK, creating a unique opportunity for significant impact on the delivery of clinical service to cancer patients. The Cancer Institute includes the Cancer... Research UK and UCL Cancer Trials Centre which is one of the largest cancer trials centres in the UK conducting multi-centre national and international phase III trials, feasibility studies and early phase I and II studies. Also embedded within the UCL Cancer Institute, the CRUK-UCL Centre provides essential infrastructure to support cancer research within UCL and is a major catalyst in the success of UCL in integrating translational and clinical cancer research with excellent basic science. Furthermore, the Institute offers educational programmes that reflect the depth and breadth of research expertise that include BSc Cancer Biomedicine, iBSc Oncology, MSc Cancer and PhD studies.
Further Information about the UCL Cancer Institute can be found on our website https://www.ucl.ac.uk/cancer
About the role
Applications are invited for a post-doctoral researcher to work in the Cancer Immunology Unit within the groups of Professor Sergio Quezada. The applicant will have the opportunity to join an exciting CRUK research programme aimed at evaluating the activity of immunomodulatory antibodies, such as checkpoint inhibitors and T-regulatory cell depleters, in the glioblastoma and lung cancer tumour microenvironment. The post-holder will be expected to utilise both in vivo murine models (70%) and ex vivo patient-derived tissue models (30%).
The candidate should ideally have an interest and experience in cancer immunology and have worked previously on immunotherapeutic modulation of the innate immune system in mouse models of lung and brain cancer. This role will also benefit those with significant experience in spectral flow cytometry.
Applications should include a CV and a Cover Letter: In the Cover Letter please evidence the essential and desirable criteria in the Person Specification part of the Job Description. (By including a Cover Letter, you can leave blank the 'Why you have applied for this role' field in the application form, which is limited in the number of characters it will allow.)
Appointment at Grade 7 (£43,124 - £51,610 per annum) is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £38,357-£41,005 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.
The post is available for 2 years in the first instance. Successful candidates will have the option to secure further funding beyond the initial funding period.
About you
The post-holder will have a PhD in Cancer Immunology (please see above for appointment details pre and post PhD submission).
The post-holder will have knowledge and experience within the area(s) of cancer immunology, murine models of lung cancer, the innate immune system, and immunotherapeutic modulation of cancer as well as evidence of participation in publications.
Please see the job description for a full person specification for the role - this can be found at the bottom of the page
What we offer
As well as the exciting opportunities this role presents, we also offer great benefits. Please visit https://www.ucl.ac.uk/work-at-ucl/rewards-and-benefits to find out more.
Our commitment to Equality, Diversity and Inclusion
As London's Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world's talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.
We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL's workforce.
These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women
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