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Scientist I, Tissue Dissociation Sorting at Flagship Pioneering, Inc.
Cambridge, United Kingdom


Job Descrption

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform human health and sustainability?

Company Summary:
Quotient Therapeutics, Inc. is a privately held, early-stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need.

Quotient Therapeutics, Inc. was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA) Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS). To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.

Position Summary:

We are seeking a biologist to support development of Quotient’s tissue dissociation and cell sorting capabilities. The role involves understanding the biology of various chronic and acute diseases, in particular the tissues and cell types involved, and developing protocols for the identification and isolation of different populations of cells and nuclei from human tissue. The ideal candidate brings enthusiasm, intellectual curiosity, scientific rigor, and a deep-rooted desire to innovate. This role is based in the vicinity of Cambridge UK and will be primarily in-person. All applicants will require permission to work in the UK.

Responsibilities:

  • Be an active member of the assay development team, conducting bench-based experiments.
  • Designing or adapting tissue dissociation and cell/nuclei isolation methods to meet project goals, and explore new technologies at the cutting-edge of the field
  • Design, test and refine experimental protocols for compatibility with cells or nuclei from diverse human tissues, including methods to select specific types of cells/nuclei based on molecular markers
  • Explore the scientific literature to support development of novel tools/methods to support Quotient’s overarching goals, independently proposing, then designing and executing sets of experiments.
  • Provide supervision and training for more junior lab members and/or technicians.
  • Maintain detailed records of results and communicate key findings to stakeholders across the company, both in written and presentation formats.
  • Work closely with contract research organisations (CROs) to outsource work as appropriate.
  • Collaborate closely with other team members across the organization.

Key Qualifications:

  • Either:
    • A Master’s degree plus 4 years of research experience in molecular/cell biology or a related field
    • A PhD in molecular/cell biology or a related field.
  • Scientific expertise in tissue dissociation, cell type identification and sorting methods such as FACS.
  • Broad understanding of tissue and cell biology.
  • Ability to work both quickly and diligently, completing high-quality work on schedule.
  • Excellent verbal and written communication.
  • Ability to work successfully in a matrix environment, where tasks may be assigned by people other than your direct line manager.
  • Ability to prioritize and manage multiple tasks simultaneously, and balance competing priorities effectively.
  • A high degree of energy, accuracy and attention to detail, and a passion for contributing to work leading to the creation of transformative medicines for patients with serious diseases.
  • Candidates with experience in some of the following areas will be preferred: (a) Working with human tissues, (b) Nuclei isolation and sorting.

Location: Cambridge, UK

Join Our Innovative Biotech Venture:

At Quotient Therapeutics, we're not just a team; we're pioneers on a mission to revolutionise the biotech landscape. Nestled in the vibrant outskirts of Cambridge, our company is all about innovative thinking and collaborative spirit.

What We Offer:

  • A Crucible of Innovation: Dive into a world where your ideas matter. Our work environment is dynamic, encouraging creativity and out-of-the-box thinking. Here, every voice contributes to our groundbreaking solutions.
  • Professional Growth in a Supportive Environment: While we're small, our aspirations are big. You'll have the unique opportunity to grow with us, learning new skills and tackling diverse challenges every day. Your growth is our growth.
  • Competitive Compensation: We understand the value of our team. That's why we offer competitive salaries that match your expertise and contribution to our shared goals.
  • Above Standard Facilities: Our labs and workspaces are more than just functional. Enjoy working in above-standard facilities that stand out in the start-up world, fostering both comfort and innovation.
  • Located at the Heart of Biotech Innovation: Our location isn't just a place; it's a strategic advantage. Situated near Cambridge, you'll be at the crossroads of biotech innovation and a thriving, intellectually stimulating community.
  • Making a Difference: Here, your work transcends the ordinary. We're about making a tangible, positive impact on the world through our biotech advancements.
  • Equality, Diversity, and Inclusion Aware: We're committed to creating a workplace where everyone feels valued and respected. While our formal ED&I statement is still in the works, we're actively aware and integrating these principles into our daily operations.
  • While we are still growing and enhancing our benefits package, we believe that the opportunity to be a part of a transformative team in a rapidly evolving industry is a rewarding experience in itself. If you're ready to make a significant impact and grow with us, we'd love to hear from you.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.


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