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Histology R&D Lead at Flagship Pioneering, Inc.
Cambridge, United Kingdom


Job Descrption

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform human health and sustainability?

Position Summary:

We are seeking an experienced biologist to lead development of Quotient’s histology and tissue profiling capabilities. The role requires a deep understanding of the biology of various chronic and acute diseases, in particular the tissues and cell types involved. The successful candidate will lead a team of scientists to develop bespoke methods for phenotyping and isolating cells of interest, for example via immunohistochemistry (IHC) on fixed tissue slices, or dissociation and cell/nuclei sorting. The ideal candidate brings creativity, scientific rigor, and a deep-rooted desire to innovate, as a well as a proven ability to manage a high-performing team to deliver ambitious research goals. This role is based in the vicinity of Cambridge UK and will be primarily in-person. All applicants will require permission to work in the UK.

Responsibilities:

  • Lead tissue profiling R&D within the Assay Development team.
  • Line manage a small team of scientists, ensuring they remain inspired and highly motivated to deliver on company goals.
  • Plan, design and direct large, high-impact research projects in the areas of tissue/cell preparation and profiling.
  • Thought leader for development and onboarding of cutting edge tissue profiling techniques.
  • Manage cross-functional teams to deliver complex projects, modelling good practice in project management.
  • Explore the scientific literature and propose innovative new tools/methods to support Quotient’s overarching goals.
  • Work closely with contract research organisations (CROs) to deliver projects on time and on budget.
  • Perform bench-based experiments to drive delivery of particularly complex projects.
  • Advise senior management on strategic decision-making.
  • Oversee roll-out of new protocols to the production team.

Key Qualifications:

  • Either:
    • A Master’s degree plus 10 years of research experience in tissues R&D or
    • A PhD in molecular/cell/tissue biology or a related field, plus 6 years of relevant post-PhD experience
  • Deep understanding of tissue and cell biology, and experience working with a range of human tissue and cell types.
  • Scientific expertise in tissue preparation and profiling methods such as histology, immunohistochemistry, tissue dissociation and FACS.
  • Evidence of an ability to devise novel solutions to research challenges and drive technological innovation.
  • Experience with line management of research scientists.
  • Exceptional verbal and written communication skills, including preparation and delivery of high quality presentations.
  • Excellent project planning and prioritization skills, and a proven ability to balance competing priorities.
  • Ability to work successfully in a matrix environment, where tasks may be assigned by people other than your direct line manager.
  • An understanding of next generation sequencing methods.
  • A high degree of energy, accuracy and attention to detail, and a passion for contributing to work leading to the creation of transformative medicines for patients with serious diseases.

Location: Cambridge, UK

Join Our Innovative Biotech Venture:

At Quotient Therapeutics, we're not just a team; we're pioneers on a mission to revolutionise the biotech landscape. Nestled in the vibrant outskirts of Cambridge, our company is all about innovative thinking and collaborative spirit.

What We Offer:

  • A Crucible of Innovation: Dive into a world where your ideas matter. Our work environment is dynamic, encouraging creativity and out-of-the-box thinking. Here, every voice contributes to our groundbreaking solutions.
  • Professional Growth in a Supportive Environment: While we're small, our aspirations are big. You'll have the unique opportunity to grow with us, learning new skills and tackling diverse challenges every day. Your growth is our growth.
  • Competitive Compensation: We understand the value of our team. That's why we offer competitive salaries that match your expertise and contribution to our shared goals.
  • Above Standard Facilities: Our labs and workspaces are more than just functional. Enjoy working in above-standard facilities that stand out in the start-up world, fostering both comfort and innovation.
  • Located at the Heart of Biotech Innovation: Our location isn't just a place; it's a strategic advantage. Situated near Cambridge, you'll be at the crossroads of biotech innovation and a thriving, intellectually stimulating community.
  • Making a Difference: Here, your work transcends the ordinary. We're about making a tangible, positive impact on the world through our biotech advancements.
  • Equality, Diversity, and Inclusion Aware: We're committed to creating a workplace where everyone feels valued and respected. While our formal ED&I statement is still in the works, we're actively aware and integrating these principles into our daily operations.
  • While we are still growing and enhancing our benefits package, we believe that the opportunity to be a part of a transformative team in a rapidly evolving industry is a rewarding experience in itself. If you're ready to make a significant impact and grow with us, we'd love to hear from you.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.


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