What if... We could harness the power of Flagship’s scientific platforms and create novel treatment options that benefit more patients, sooner?

Pioneering Medicines, an initiative of Flagship Pioneering, is building a world-class biopharmaceutical R&D capability focused on conceiving and developing life-changing treatments for patients by harnessing the power of Flagship's scientific platforms and applying those innovative approaches to serious diseases with unmet medical need. Unique to Pioneering Medicines’ approach is the opportunity to combine platforms to create truly novel and potentially transformative treatments. 

About Flagship Pioneering:

Flagship Pioneering conceives, creates, resources, and develops first-in-category life science platform companies to transform human health and sustainability. Since its founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents.  

Position Summary:

We are seeking a Research Associate or Senior Research Associate Contractor who will be responsible for developing and performing in vitro studies for mechanism of action and efficacy of novel biological and/or small molecule therapeutic agents, including nucleic based approaches to support drug discovery efforts across multiple programs from target validation to human translation.

The ideal candidate will be skillful in cell-based assays with cell lines as well as primary cells from rodent, NHP and human origin. Previous in vitro experience with primary cells (eg: adipocytes, myotubes, hepatocytes etc.) is highly desired. The position will require ability to work in a fast-paced environment on multiple tasks, quickly learn new techniques, organize tasks efficiently and keep records accurately. Ability to interact well with scientific colleagues and work effectively in a team-oriented environment will be necessary.

This role is a 12 month contract. Pioneering Medicines 3rd party agency will be hiring for this position. Employees under this position with be working at Pioneering Medicines as a contractor with the possibility to convert to a full-time Pioneering Medicines employee based on performance and other criteria in the future. 

Responsibilities:

• Perform laboratory-based assays in BSL2/ BSL2+ environment for validation of potential drug development targets and to characterize diverse therapeutics.
• Independently conduct experiments and analyze data.
• Operate and maintain the relevant equipment.
• Maintain electronic notebook.

Requirements:

• Bachelor or Master of Science degree with a minimum of 2 years’ experience in a laboratory of academia or industry. Industrial experience is preferred (PhD is not excluded)
• Prior working experience with in vitro cell based pharmacology assays using human or rodent primary cells.
• Proficient in assay development for testing compounds across different modalities.
• Hands-on experience with cell-based and molecular biology assays, such as flow cytometry, immunoblot, ELISA/MSD and qPCR etc.
• Experience of in vitro testing of LNPs is highly desired.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.